Induction of osteogenic differentiation in a rat calvarial bone defect model using an In situ forming graphene oxide incorporated glycol chitosan/oxidized hyaluronic acid injectable hydrogel

Graphene oxide (GO) incorporated hydrogels have received great attention and have shown excellent potential for use in the field of bone tissue engineering due to their unique osteogenic functionalities. However, current hydrogel systems are limited in their ability to provide an appropriate amount of GO to the lesion area. To overcome this issue, we designed a GO incorporated glycol chitosan (gC)-hyaluronic acid (HA) injectable hydrogel system...