Stromal-Immune Cell Crosstalk Maintains Type 2 Immune Cell Populations within Visceral Adipose Tissue
Abstract
Type 2 immune cells are key to the maintenance of healthy adipose tissue, however the cues responsible for the establishment and maintenance of adipose type two immune cells remain unclear. Rana et al. report a specialized stromal cell produces interleukin-33 (IL-33) that activates group 2 innate lymphoid cells (ILC2s). Activated ILC2s in turn produce type two cytokines that elicit further IL-33 production by the stroma in a positive feedback...
Paper Details
Title
Stromal-Immune Cell Crosstalk Maintains Type 2 Immune Cell Populations within Visceral Adipose Tissue
Published Date
May 6, 2020
Journal
Volume
2
Issue
3
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