When Separation Causes Activation: Biophysical Control of Bulk Autophagy Initiation
Abstract
Fujioka et al., 2020Fujioka Y. Alam J.M. Noshiro D. Mouri K. Ando T. Okada Y. May A.I. Knorr R.L. Suzuki K. Ohsumi Y. Noda N.N. Phase separation organizes the site of autophagosome formation.Nature. 2020; 578: 301-305Crossref Scopus (161) Google Scholar uncovered liquid-liquid phase separation of the PAS, a key driver of autophagosome formation in yeast. Moreover, the authors demonstrated that liquid-like PAS controls autophagic kinase...
Paper Details
Title
When Separation Causes Activation: Biophysical Control of Bulk Autophagy Initiation
Published Date
May 1, 2020
Journal
Volume
78
Issue
3
Pages
379 - 381
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