IgE‐mediated regulation of IL‐10 and type I IFN enhances rhinovirus‐induced Th2 differentiation by primary human monocytes

Rhinovirus (RV) infections are linked to the development and exacerbation of allergic diseases including allergic asthma. IgE, another contributor to atopic disease pathogenesis, has been shown to regulate DC antiviral functions and influence T cell priming by monocytes. We previously demonstrated that IgE‐mediated stimulation of monocytes alters multiple cellular functions including cytokine secretion, phagocytosis, and influenza‐induced Th1...