Polymyxin Delivery Systems: Recent Advances and Challenges
Abstract
Polymyxins are vital antibiotics for the treatment of multiresistant Gram-negative ESKAPE pathogen infections. However, their clinical value is limited by their high nephrotoxicity and neurotoxicity, as well as their poor permeability and absorption in the gastrointestinal tract. This review focuses on various polymyxin delivery systems that improve polymyxin bioavailability and reduce drug toxicity through targeted and controlled release....
Paper Details
Title
Polymyxin Delivery Systems: Recent Advances and Challenges
Published Date
Apr 29, 2020
Journal
Volume
13
Issue
5
Pages
83 - 83
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