Harnessing proteases for T regulatory cell immunotherapy

Volume: 50, Issue: 6, Pages: 770 - 778
Published: Jun 1, 2020
Abstract
The immune system is tightly regulated by a subset of T cells defined as regulatory T cells (Tregs). Tregs maintain immune homeostasis by restraining unwarranted immune cell activation and effector function. Here, we discuss an important but underappreciated role of proteases in controlling Treg function. Proteases regulate a number of vital processes that determine T cell immune responses and some of them such as furin, ADAM (through regulating...
Paper Details
Title
Harnessing proteases for T regulatory cell immunotherapy
Published Date
Jun 1, 2020
Volume
50
Issue
6
Pages
770 - 778
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