Outside Back Cover: (Biotechnology Journal 5/2020)

A Chinese hamster ovary (CHO) cell clone is created by precisely placing a gene cassette into a specific chromosomal location via clustered regularly interspaced short palindromic repeats (CRISPR)-Cas9. The location is chosen based on transcriptome analysis to ensure stable and high-level expression of an antibody or a protein gene of interest. One of the applications is that the gene of a target antibody or protein can be readily inserted into...