Sestrin2 modulates cardiac inflammatory response through maintaining redox homeostasis during ischemia and reperfusion

Volume: 34, Pages: 101556 - 101556
Published: Jul 1, 2020
Abstract
Ischemia heart disease is the leading cause of death world-widely and has increased prevalence and exacerbated myocardial infarction with aging. Sestrin2, a stress-inducible protein, declines with aging in the heart and the rescue of Sestrin2 in the aged mouse heart improves the resistance to ischemic insults caused by ischemia and reperfusion. Here, through a combination of transcriptomic, physiological, histological, and biochemical...
Paper Details
Title
Sestrin2 modulates cardiac inflammatory response through maintaining redox homeostasis during ischemia and reperfusion
Published Date
Jul 1, 2020
Volume
34
Pages
101556 - 101556
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