The Gut Microbiota: Emerging Evidence in Autoimmune Diseases

The compositional and functional changes of gut microbiota have been implicated in various autoimmune diseases (AIDs) by high-throughput techniques such as metagenomic sequencing. Correlation studies in humans and interventional studies in animal models have suggested that disturbed gut microbiota is involved in the immunopathogenesis of AIDs. The mechanisms of disturbed gut microbiota include abnormal microbial translocation, molecular mimicry,...