Early Anxiety, Depressive, and Post-Traumatic Stress Symptoms Impact Cortical Thinning Trajectories Throughout Adolescence

Adolescence is a sensitive period for the development and emergence of anxiety and mood disorders. Moreover, research suggests that symptoms ranging from subclinical-to-clinical levels are related to pathological changes in cortical gray matter across dispersed brain regions. However, much of the research has been cross-sectional, limiting researchers’ ability to fully understand the neurodevelopmental impacts of these symptoms. The present...