Oncostatin M Induction of Monocyte Chemoattractant Protein 1 is Inhibited by Anti-oncostatin M Receptor Beta Monoclonal Antibody KPL-716
Volume: 100, Issue: 14, Pages: adv00197 - adv00197
Published: Jan 1, 2020
Abstract
To evaluate cellular response to oncostatin M (OSM) in comparison to interleukin (IL)-31, we analyzed monocyte chemoattractant protein 1 (MCP-1) as a readout for OSM responses with and without IL-4, IL-13, anti-OSM receptor ? monoclonal antibody KPL-716, and anti?IL-31 receptor ? antibody in human epidermal keratinocytes and human dermal fibroblasts in vitro. In human epidermal keratinocytes, OSM significantly induced STAT3 or STAT1...
Paper Details
Title
Oncostatin M Induction of Monocyte Chemoattractant Protein 1 is Inhibited by Anti-oncostatin M Receptor Beta Monoclonal Antibody KPL-716
Published Date
Jan 1, 2020
Journal
Volume
100
Issue
14
Pages
adv00197 - adv00197
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