Molecular mechanism of light-driven sodium pumping

Volume: 11, Issue: 1
Published: May 1, 2020
Abstract
The light-driven sodium-pumping rhodopsin KR2 from Krokinobacter eikastus is the only non-proton cation active transporter with demonstrated potential for optogenetics. However, the existing structural data on KR2 correspond exclusively to its ground state, and show no sodium inside the protein, which hampers the understanding of sodium-pumping mechanism. Here we present crystal structure of the O-intermediate of the physiologically relevant...
Paper Details
Title
Molecular mechanism of light-driven sodium pumping
Published Date
May 1, 2020
Volume
11
Issue
1
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