Base editing goes into hyperdrive
Abstract
CRISPR base editors can induce single-base-pair changes in the genome, although they are often inefficient. A study now shows that fusion of the DNA-binding domain of RAD51 to base editors enhances both the efficiency and the targeting range of optimized enzymes. These ‘hyper-editors’ offer effective tools for disease modeling and gene...
Paper Details
Title
Base editing goes into hyperdrive
Published Date
May 11, 2020
Journal
Volume
22
Issue
6
Pages
617 - 618
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