In-situ monitoring of glucose metabolism in cancer cell microenvironments based on hollow fiber structure

Cancer cells alter their metabolism to promote rapid proliferation, resulting in significant amounts of glucose to be used for aerobic glycolysis in the tumor microenvironment. Due to the spatial mismatch between electrodes and cells, existing methods for evaluating cancer cell metabolism lack kinetic and microenvironmental information. In this paper, we present a hollow fiber structure loaded with sensing elements as a long-term cellular...