Gene Expression of Kallikreins in Breast Cancer Cell Lines

Background/Aim: This study analyzed the gene expression of the “classic” KLK1 and “new” kallikreins KLK4-KLK15, in relation to the molecular characteristics and in vitro invasiveness of 21 breast cancer (BC) and three normal breast-derived cell lines (CLs). Materials and Methods: Gene expression of KLKs was determined by using real-time polymerase chain reaction (PCR). The invasiveness of the CLs was examined using a fibroblast-collagen-based in...