Chemical Synthesis and Isolation of Trans ‐Palmitoleic Acid ( Trans ‐C16:1 n‐7) Suitable for Nutritional Studies

Trans ‐palmitoleic acid ( trans ‐9 C16:1, or trans ‐C16:1 n‐7, TPA) is typically found in ruminant‐derived foods (milk and meat). Of note, previous epidemiological studies associated high levels of circulating TPA with a lower risk of type 2 diabetes and metabolic syndrome in humans. At the current time, TPA intakes in humans are ensured by ruminant‐derived foods. However, due to the very low commercial availability of TPA, there are no...