Structural basis for Ca2+-dependent activation of a plant metacaspase
Abstract
Plant metacaspases mediate programmed cell death in development, biotic and abiotic stresses, damage-induced immune response, and resistance to pathogen attack. Most metacaspases require Ca 2+ for their activation and substrate processing. However, the Ca 2+ -dependent activation mechanism remains elusive. Here we report the crystal structures of Metacaspase 4 from Arabidopsis thaliana ( At MC4) that modulates Ca 2+ -dependent, damage-induced...
Paper Details
Title
Structural basis for Ca2+-dependent activation of a plant metacaspase
Published Date
May 7, 2020
Journal
Volume
11
Issue
1
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