Methods for Population Adjustment with Limited Access to Individual Patient Data: A Review and Simulation Study
Abstract
Population-adjusted indirect comparisons estimate treatment effects when access to individual patient data is limited and there are cross-trial differences in effect modifiers. Popular methods include matching-adjusted indirect comparison (MAIC) and simulated treatment comparison (STC). There is limited formal evaluation of these methods and whether they can be used to accurately compare treatments. Thus, we undertake a comprehensive simulation...
Paper Details
Title
Methods for Population Adjustment with Limited Access to Individual Patient Data: A Review and Simulation Study
Published Date
Apr 30, 2020
Journal
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