mTOR/NF-κB signaling pathway protects hippocampal neurons from injury induced by intermittent hypoxia in rats

Volume: 131, Issue: 10, Pages: 994 - 1003
Published: May 14, 2020
Abstract
To expound the roles of mTOR and NF-kB signaling pathway in intermittent hypoxia (IH)-induced damage of hippocampal neurons.For rat experiments, mTOR inhibitor (Rapamycin, Rapa) and NF-κB signaling inhibitor (ammonium pyrrolidine dithiocarbamate, PDTC) were applied to inhibit mTOR and NF-κB signaling, respectively. For neuron experiments, hippocampal neurons from rat were successfully cultured. Different concentrations of Rapa and PDTC were...
Paper Details
Title
mTOR/NF-κB signaling pathway protects hippocampal neurons from injury induced by intermittent hypoxia in rats
Published Date
May 14, 2020
Volume
131
Issue
10
Pages
994 - 1003
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