Dopamine D3 receptor-based medication development for the treatment of opioid use disorder: Rationale, progress, and challenges
Abstract
Opioid abuse and related overdose deaths continue to rise in the United States, contributing to the current national opioid crisis. Although several opioid-based pharmacotherapies are available (e.g., methadone, buprenorphine, naloxone), they show limited effectiveness in long-term relapse prevention. In response to the opioid crisis, the National Institute on Drug Abuse proposed a list of pharmacological targets of highest priority for...
Paper Details
Title
Dopamine D3 receptor-based medication development for the treatment of opioid use disorder: Rationale, progress, and challenges
Published Date
Jul 1, 2020
Volume
114
Pages
38 - 52
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