Wnts and the hallmarks of cancer
Abstract
Since the discovery of the first mammalian Wnt proto-oncogene in virus-induced mouse mammary tumors almost four decades ago, Wnt signaling pathway and its involvement in cancers have been extensively investigated. Activation of this evolutionarily conserved pathway promotes cancer development via diverse mechanisms. Cancer is a complex disease and one outstanding conceptual framework for understanding its biology is the Hallmarks of Cancer. In...
Paper Details
Title
Wnts and the hallmarks of cancer
Published Date
May 8, 2020
Volume
39
Issue
3
Pages
625 - 645
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