Signaling pathway deregulation and molecular alterations across pediatric medulloblastomas
Abstract
Medulloblastomas (MBs) account for 15% of brain tumors in children under the age of 15. To date, the overall 5-year survival rate for all children is only around 60%. Recent advances in cancer genomics have led to a fundamental change in medulloblastoma classification and is evolving along with the genomic discoveries, allowing to regularly reclassify this disease. The previous molecular classification defined 4 groups (WNT-activated MB,...
Paper Details
Title
Signaling pathway deregulation and molecular alterations across pediatric medulloblastomas
Published Date
Feb 1, 2021
Journal
Volume
67
Issue
1
Pages
39 - 45
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