HLA alleles associated with asparaginase hypersensitivity in childhood ALL: a report from the DFCI Consortium
Abstract
Aim: To evaluate the association between human leukocyte antigen (HLA) alleles and native Escherichia coli asparaginase hypersensitivity (AH) in children with acute lymphoblastic leukemia (ALL) who received Dana-Farber Cancer Institute treatment protocols. Patients & methods: HLA-DQA1, HLA-DRB1 and HLA-DQB1 alleles were retrieved from available whole exome sequencing data of a subset of childhood ALL patients from Quebec ALL cohort and...
Paper Details
Title
HLA alleles associated with asparaginase hypersensitivity in childhood ALL: a report from the DFCI Consortium
Published Date
Jun 1, 2020
Journal
Volume
21
Issue
8
Pages
541 - 547
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