The Serum MicroRNA Signatures for Pancreatic Cancer Detection and Operability Evaluation

Pancreatic cancer (PC) has high morbidity and mortality and is considered to be the fourth leading cause of cancer death. Its diagnosis and treatment are difficult. Liquid biopsy makes early diagnosis of pancreatic cancer possible. We expression profiles of 2,555 serum miRNAs in 100 pancreatic cancer patients and 150 healthy controls. With advanced feature selection methods, we identified 13 pancreatic cancer signature miRNAs that can classify...