Comparative Pharmacokinetics of Δ9-Tetrahydrocannabinol in Adolescent and Adult Male Mice
Volume: 374, Issue: 1, Pages: 151 - 160
Published: Apr 28, 2020
Abstract
We investigated the pharmacokinetic properties of Δ9-tetrahydrocannabinol (Δ9-THC), the main psychoactive constituent of cannabis, in adolescent and adult male mice. The drug was administered at logarithmically ascending doses (0.5, 1.6, and 5 mg/kg, i.p.) to pubertal adolescent (37-day-old) and adult (70-day-old) mice. Δ9-THC and its first-pass metabolites—11-hydroxy-Δ9-THC and...
Paper Details
Title
Comparative Pharmacokinetics of Δ9-Tetrahydrocannabinol in Adolescent and Adult Male Mice
Published Date
Apr 28, 2020
Volume
374
Issue
1
Pages
151 - 160
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