Exploratory analysis of age and sex dependent DNA methylation patterns on the X-chromosome in whole blood samples

Volume: 12, Issue: 1
Published: Apr 28, 2020
Abstract
Large numbers of autosomal sites are found differentially methylated in the aging genome. Due to analytical difficulties in dealing with sex differences in X-chromosome content and X-inactivation (XCI) in females, this has not been explored for the X chromosome.Using data from middle age to elderly individuals (age 55+ years) from two Danish cohorts of monozygotic twins and the Scottish Lothian Birth Cohort 1921, we conducted an...
Paper Details
Title
Exploratory analysis of age and sex dependent DNA methylation patterns on the X-chromosome in whole blood samples
Published Date
Apr 28, 2020
Volume
12
Issue
1
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