Mental status and physical activity in patients with homozygous familial hypercholesterolemia: A subgroup analysis of a nationwide survey (A-HIT1 registry)

•HoFH patients with any cardiovascular condition have more psychiatric symptoms. •Lower age of first coronary event is related to better psychiatric status. •HoFH patients with better mental state are more likely to exercise regularly. Background Homozygous familial hypercholesterolemia (HoFH) is a rare, life-threatening disease due to high serum low-density lipoprotein (LDL) cholesterol levels. LDL cholesterol–lowering interventions are...