Type-2 diabetes and risk of dementia: observational and Mendelian randomisation studies in 1 million individuals

In observational studies, type-2 diabetes is associated with increased risk of dementia; however, the causal nature of this association remains unanswered. In an unselected nationwide study of all Danes, we wanted to test whether type-2 diabetes is associated with dementia subtypes, and to test whether potential associations are of a causal nature.In the current study of nationwide observational registry data in all Danes above the age of 65...