Experimental Methodologies for the Visualization of Cardiac Myofiber Orientations within Perfusion‐fixed Human Hearts

Cardiac myofiber structure and organizations play critical roles in the electrical and mechanical properties of the heart. Diffusion tensor magnetic resonance imaging (DTMRI) has been a useful imaging modality to visualize the myocardial fiber orientation with emerging clinical application. DTMRI takes advantage of the limited diffusion of water along the cardiac fiber’s longitudinal axis and provides the dominant direction of diffusion [1] ....