Novel class of OTU deubiquitinases regulate substrate ubiquitination upon Legionella infection
Abstract
Legionella pneumophila is a gram-negative pathogenic bacterium that causes Legionaries’ disease. The Legionella genome codes more than 300 effector proteins able to modulate host-pathogen interactions during infection. Among them are also enzymes altering the host-ubiquitination system including bacterial ligases and deubiquitinases. In this study, based on homology-detection screening on 305 Legionella effector proteins, we identified two L...
Paper Details
Title
Novel class of OTU deubiquitinases regulate substrate ubiquitination upon Legionella infection
Published Date
Apr 25, 2020
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