Recent advances in the chemistry of iron-based chemotherapeutic agents

The discovery of cisplatin followed by its success in anticancer therapy laid the foundation of metal-based drug design and development. Further research led to discovery of other platinum containing complexes, namely, carboplatin and oxaliplatin. The disadvantages of the platinum-based drugs are their untoward side effects and drug resistance. This paved way for new metal-based anticancer drugs with a prospect for iron-based anticancer agents....