Low-intensity pulsed ultrasound inhibits IL-1β-induced inflammation of fibroblast-like synoviosytes via NF-κB pathway

Osteoarthritis (OA) is a degenerative joint disease, which is usually accompanied by inflammation. The aim of this study was to evaluate the anti-inflammatory effect of Low-intensity pulsed ultrasound (LIPUS) on OA. Fibroblast-Like Synoviocyte (FLS) were stimulated by LIPUS with/without interleukin (IL)-1β to evaluate inflammatory responses. The results showed that IL-1β could effectively induce the production of nitric oxide (NO), prostaglandin...