Establishment of immortalised cell lines derived from female Shiba goat KNDy and GnRH neurones

Kisspeptin plays a critical role in governing gonadotrophin‐releasing hormone (GnRH)/gonadotrophin secretion and subsequent reproductive function in mammals. The hypothalamic arcuate nucleus (ARC) kisspeptin neurones, which co‐express neurokinin B (NKB) and dynorphin A (Dyn) and are referred to as KNDy neurones, are considered to be involved in GnRH generation. The present study aimed to establish cell lines derived from goat KNDy and GnRH...