De novo damaging variants associated with congenital heart diseases contribute to the connectome
Abstract
Congenital heart disease (CHD) survivors are at risk for neurodevelopmental disability (NDD), and recent studies identify genes associated with both disorders, suggesting that NDD in CHD survivors may be of genetic origin. Genes contributing to neurogenesis, dendritic development and synaptogenesis organize neural elements into networks known as the connectome. We hypothesized that NDD in CHD may be attributable to genes altering both neural...
Paper Details
Title
De novo damaging variants associated with congenital heart diseases contribute to the connectome
Published Date
Apr 27, 2020
Journal
Volume
10
Issue
1
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