Ethanol consumption inhibits TFH cell responses and the development of autoimmune arthritis

Volume: 11, Issue: 1
Published: Apr 24, 2020
Abstract
Alcohol consumption is a consistent protective factor for the development of autoimmune diseases such as rheumatoid arthritis (RA). The underlying mechanism for this tolerance-inducing effect of alcohol, however, is unknown. Here we show that alcohol and its metabolite acetate alter the functional state of T follicular helper (T FH ) cells in vitro and in vivo, thereby exerting immune regulatory and tolerance-inducing properties. Alcohol-exposed...
Paper Details
Title
Ethanol consumption inhibits TFH cell responses and the development of autoimmune arthritis
Published Date
Apr 24, 2020
Volume
11
Issue
1
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