VLDL and HDL attenuate endoplasmic reticulum and metabolic stress in HL-1 cardiomyocytes
Abstract
Lipoproteins have a vital role in the development of metabolic and cardiovascular diseases ranging from protective to deleterious effects on target tissues. VLDL has been shown to induce lipotoxic lipid accumulation and exert a variety of negative effects on cardiomyocytes. Lipotoxicity and endoplasmic reticulum (ER) stress are proposed to be the mediators of damaging effects of metabolic diseases on cardiovascular system. We treated...
Paper Details
Title
VLDL and HDL attenuate endoplasmic reticulum and metabolic stress in HL-1 cardiomyocytes
Published Date
Aug 1, 2020
Volume
1865
Issue
8
Pages
158713
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