Differential Effects of Electroconvulsive Therapy in the Treatment of Major Depressive Disorder

<b><i>Background/Aims/Methods:</i></b> Electroconvulsive therapy (ECT) is still one of the most potent treatments in the acute phase of major depressive disorder (MDD) and particularly applied in patients considered treatment resistant. However, despite the frequent and widespread use of ECT for &#x3e;70 years, the exact neurobiological mechanisms underlying its efficacy remain unclear. The present review aims to...