Cytokine-like Roles for Metabolites in Immunity
Abstract
Metabolites have functions in the immune system independent of their conventional roles as sources or intermediates in biosynthesis and bioenergetics. We are still in the pioneering phase of gathering information about the functions of specific metabolites in immunoregulation. In this review, we cover succinate, itaconate, α-ketoglutarate, and lactate as examples. Each of these metabolites has a different story of how their immunoregulatory...
Paper Details
Title
Cytokine-like Roles for Metabolites in Immunity
Published Date
Jun 1, 2020
Journal
Volume
78
Issue
5
Pages
814 - 823
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