Dendritic Cell Maturation Defines Immunological Responsiveness of Tumors to Radiation Therapy

Volume: 204, Issue: 12, Pages: 3416 - 3424
Published: Jun 15, 2020
Abstract
Radiation therapy is capable of directing adaptive immune responses against tumors by stimulating the release of endogenous adjuvants and tumor-associated Ags. Within the tumor, conventional type 1 dendritic cells (cDC1s) are uniquely positioned to respond to these signals, uptake exogenous tumor Ags, and migrate to the tumor draining lymph node to initiate cross-priming of tumor-reactive cytotoxic CD8+ T cells. In this study, we report that...
Paper Details
Title
Dendritic Cell Maturation Defines Immunological Responsiveness of Tumors to Radiation Therapy
Published Date
Jun 15, 2020
Volume
204
Issue
12
Pages
3416 - 3424
Citation AnalysisPro
  • Scinapse’s Top 10 Citation Journals & Affiliations graph reveals the quality and authenticity of citations received by a paper.
  • Discover whether citations have been inflated due to self-citations, or if citations include institutional bias.