Immunotherapy, pre‐school wheeze and asthma

Although immunotherapy has been in use for over 100 years, innovations continue to be investigated to optimize this therapy.1 Examples are peptide immunotherapy, recombinant allergens, epicutaneous immunotherapy and oral immunotherapy. All of these novel approaches have been found to have shortcomings in terms of efficacy or safety. So, we continue to use subcutaneous and sublingual immunotherapy. Novel approaches are required but these should...