Insulin resistance is an independent factor to determine an exaggerated pressor response to ischemic rhythmic handgrip in non–diabetic older adults

Patients with type 2 diabetes display an exaggerated blood pressure (BP) response during exercise. However, the mechanism(s) underlying this abnormal exercise BP is poorly understood. A previous study demonstrated that the increase in muscle sympathetic nerve activity during post–exercise muscle ischemia (PEMI) is significantly associated with glucose control and insulin resistance markers such as fasting glucose, hemoglobin A1c (HbA1c), and...