Cytokine/adipokine profile shows no evidence of an inflammatory or metabolic basis for incident erosive hand oa in the osteoarthritis initiative cohort

Purpose: Erosive Hand OA (eHOA) is a painful, age-related destructive arthritis of interphalangeal joints that severely impairs manipulative activities of daily life. Observations that erosive Hand OA is often associated with generalized OA, and with clinical inflammation, have predicated conjecture of a systemic inflammo-metabolic pathogenesis. We tested for associations of inflammation and metabolic biomarkers in the OAI cohort. Methods: Using...