A novel dual-mode and label-free aptasensor based methodology for breast cancer tissue marker targeting

Tumor biomarkers are elements that are created by the tumor itself or other host cells in response to cancerous conditions. The detection of HER2, as one of these biomarkers, is important in order to prescribe Herceptin (trastuzumab). So, precise measurement of the HER2 status is vital to ensure that all patients with breast cancer who can use Herceptin are correctly identified. In this method, we used the optical properties of gold nanoclusters...