Clinical efficacy and safety of ketotifen in treating irritable bowel syndrome with diarrhea

Objective: The aim of the study was to investigate the clinical efficacy and safety of ketotifen for the treatment of irritable bowel syndrome with diarrhea (IBS-D). Methods: A total of 108 enrolled IBS-D patients were randomly divided into a ketotifen group ( n = 55) and a control (placebo) group ( n = 53). The patients in the ketotifen group received ketotifen tablets (1 mg, oral) two times daily; patients in the control group received oral...