Long-Term Outcomes With Drug-Eluting Stents or Coronary Artery Bypass Surgery for Unprotected Left Main Coronary Disease: A Meta-Analysis and Trial Sequential Analysis of Randomized Trials

Percutaneous coronary intervention (PCI) with drug-eluting stents (DES) has emerged as an acceptable revascularization strategy for select patients with unprotected left main coronary disease (LMCA).1 The EXCEL trial showed no difference between DES and coronary artery bypass surgery (CABG) at 5 years for the composite of death, procedure- and nonprocedure-related myocardial infarction (MI), or stroke2; however, all-cause mortality was higher...