External Validation of a Risk Score for Major Toxicity Among Nonsteroidal Anti‐Inflammatory Drug Users: Real‐World Application

Objective We previously derived and validated a risk score for major nonsteroidal anti‐inflammatory drug ( NSAID ) toxicity over 1 year among NSAID users in a randomized controlled trial. This work was extended to examine the risk score's performance in an external population using real‐world data. Methods Patients enrolled in the Corrona Rheumatoid Arthritis ( RA ) Registry were included if they initiated use of an NSAID . We defined the...