Modelling the impact of antibody-dependent enhancement on disease severity of Zika virus and dengue virus sequential and co-infection
Abstract
Human infections with viruses of the genus Flavivirus , including dengue virus (DENV) and Zika virus (ZIKV), are of increasing global importance. Owing to antibody-dependent enhancement (ADE), secondary infection with one Flavivirus following primary infection with another Flavivirus can result in a significantly larger peak viral load with a much higher risk of severe disease. Although several mathematical models have been developed to quantify...
Paper Details
Title
Modelling the impact of antibody-dependent enhancement on disease severity of Zika virus and dengue virus sequential and co-infection
Published Date
Apr 1, 2020
Journal
Volume
7
Issue
4
Pages
191749 - 191749
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