Anticoagulant activity and pleiotropic effects of heparin
Abstract
The recognized therapeutic effect of heparins is an anticoagulant activity (anti-Xa and anti-IIa) acting in an indirect manner (cofactor of antithrombin) but which is carried by only 20% at best of the glycan chains composing any commercial preparation of heparin, whether unfractionated or low molecular weight. However, the effects of glycan chains that participate in the therapeutic but also potentially adverse effects of heparin preparations...
Paper Details
Title
Anticoagulant activity and pleiotropic effects of heparin
Published Date
May 1, 2020
Volume
45
Issue
3
Pages
147 - 157
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