BEON: A Functional Fluorescence Reporter for Quantification and Enrichment of Adenine Base-Editing Activity
Abstract
Adenine base editor (ABE) is a new generation of genome-editing technology through fusion of Cas9 nickase with an evolved E. coli TadA (TadA∗) and holds great promise as novel genome-editing therapeutics for treating genetic disorders. ABEs can directly convert A-T to G-C in specific genomic DNA targets without introducing double-strand breaks (DSBs). We recently showed that computer program-assisted analysis of Sanger sequencing traces can be...
Paper Details
Title
BEON: A Functional Fluorescence Reporter for Quantification and Enrichment of Adenine Base-Editing Activity
Published Date
Jul 1, 2020
Journal
Volume
28
Issue
7
Pages
1696 - 1705
Citation AnalysisPro
You’ll need to upgrade your plan to Pro
Looking to understand the true influence of a researcher’s work across journals & affiliations?
- Scinapse’s Top 10 Citation Journals & Affiliations graph reveals the quality and authenticity of citations received by a paper.
- Discover whether citations have been inflated due to self-citations, or if citations include institutional bias.
Notes
History