Cross-trait analyses with migraine reveal widespread pleiotropy and suggest a vascular component to migraine headache
Volume: 49, Issue: 3, Pages: 1022 - 1031
Published: Apr 19, 2020
Abstract
Nearly a fifth of the world's population suffer from migraine headache, yet risk factors for this disease are poorly characterized.To further elucidate these factors, we conducted a genetic correlation analysis using cross-trait linkage disequilibrium (LD) score regression between migraine headache and 47 traits from the UK Biobank. We then tested for possible causality between these phenotypes and migraine, using Mendelian randomization. In...
Paper Details
Title
Cross-trait analyses with migraine reveal widespread pleiotropy and suggest a vascular component to migraine headache
Published Date
Apr 19, 2020
Volume
49
Issue
3
Pages
1022 - 1031
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